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Medicine

Antibiotic uses multiple mechanisms to avoid resistance

Researchers developed a molecule that targets bacterial cells by two different mechanisms--attacking the cell membrane and disabling folate synthesis. This molecule seems to prevent bacteria from developing antibiotic-resistance.

Redesigning the polio vaccine - Lessons from evolution

Current polio vaccines have been successful in nearly eradicating polio in the world. Unfortunately, there have been emerging cases of polio in recent years. To combat this, scientists have designed a new oral poliovirus vaccine that could result in a…

Is diabetes communicable?

CIFAR Fellows’s paper questions whether diabetes, heart attacks and strokes are actually non-communicable diseases (NCDs). Microbiota (bacteria, viruses, fungi) that spread flu, HIV/AIDS, may also carry NCDs. People with NCDs have damaged microbiota,…

Ultrasound speaker implant that can open a door to your brain

Scientists have developed a biodegradable ultrasound speaker that can be placed inside the brain. When activated, it makes the blood-brain barrier permeable, potentially allowing certain drugs such as brain cancer chemotherapy and antidepressants to…

New migraine medication passes clinical trial

A new migraine medication called ubrogepant recently passed a large scale phase 3 clinical trial. This medication may be able to help treat patients that cannot tolerate or do not respond to the most common types of migraine medication.

Virtual Clinical Trials: Testing new drugs from afar

by Isabella Grabski figures by Jovana Andrejevic Clinical trials are critical to study the safety and effectiveness of new drugs, but they are no small endeavor. The cost of a clinical trial can range anywhere from $7 million to over $50 million, and…