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Medicine

Antibiotic Persistence and Resistance

by Molly Sargen Antibiotics are drugs that kill or inhibit the growth of microbes, including bacteria and fungi. These drugs work by blocking essential processes like protein production, DNA replication, and cell division. After Alexander Fleming’s…

Mapping Individual Microbes among the Multitudes

by Sophia Swartzfigures by Jasmin Joseph-Chazan If you put all of the living things on Earth in a box–from humans to anteaters to teeny-tiny tardigrades–and then plucked one of these organisms out at random, it is very, very likely that you just found…

Grand Evolutionary Transitions: The eruption of multicellularity

by Piyush Nandafigures by Corena Loeb Around 600 million years ago, single-celled life transitioned to multicellular life forms, begetting a paradigm shift in the definition of life on earth. This was an event so remarkable in earth’s timeline that it…

Mining DNA for Disease Prediction: The polygenic risk score

by Alex Yenkinfigures by Allie Elchert Long before the completion of the Human Genome Project, scientists knew that many common diseases had a genetic component. However, there was debate about the architecture of these genetic effects: were there a…

James E. Bowman: Making history in science and society

by Tian Lu James Edward Bowman was born in Washington, D.C. on February 5, 1923. He grew up in a segregated environment which he described saying “there was complete segregation. … One could only go to theaters, movies, restaurants in the black…

Rebecca Lee Crumpler: Physician, Author, Pioneer

Jaclyn Long is a first year Ph.D. student in the Immunology Program at Harvard Medical School. Abby Knecht is a second year graduate student in the Molecules Cells and Organisms program at Harvard University where she is studying self versus non-self…

Rebecca Lee Crumpler: Physician, Author, Pioneer

Rebecca Lee Crumpler was born in Delaware in 1831. She was raised by her aunt in Pennsylvania, who often spent time caring for sick neighbors. Inspired by her aunt, Crumpler began working as a nurse in Charlestown, Massachusetts in 1852. During her eight…