Skip to main content

genes

Mining DNA for Disease Prediction: The polygenic risk score

by Alex Yenkinfigures by Allie Elchert Long before the completion of the Human Genome Project, scientists knew that many common diseases had a genetic component. However, there was debate about the architecture of these genetic effects: were there a…

Why Drugs Tested in Mice Fail in Human Clinical Trials

by Sam Zimmerman  figures by Hannah Zucker If we were all mice, Alzheimer’s disease, cancer, diabetes, and most inherited disorders would be a thing of the past. We could nibble on as much cheese as we wanted without fear of heart disease and run around…

Zombie genes help eradicate elephant cancer in early stages

Let’s consider a paradox of probabilities. If all cells have the same risk of becoming cancerous, then the likelihood of developing cancer is proportional to the number of cells in an animal. This argument generally holds true for the incidence of cancer…