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drug development

Nature Teaches Us How to Edit DNA

By studying how the cell repairs DNA damage, researchers have developed a new technology to edit large DNA fragments in bacteria cells.

A Potential Male Oral Birth Control Pill may be on the Horizon

Oral contraceptive pills are currently only available for women. Recently, a compound purified from a Chinese herb is found to have the ideal properties of a male contraceptive drug: efficient, reversible and non-toxic. Could a male birth control pill…

Why Drugs Tested in Mice Fail in Human Clinical Trials

by Sam Zimmerman  figures by Hannah Zucker If we were all mice, Alzheimer’s disease, cancer, diabetes, and most inherited disorders would be a thing of the past. We could nibble on as much cheese as we wanted without fear of heart disease and run around…

Organs-on-Chips: A promising future for therapeutic drugs

by Garrett Dunlap figures by Rebecca Clements  It’s no secret – pharmaceuticals are expensive for the patients who need them. One major reason for this is the cost and time needed to bring a drug to market. In our current medication pipeline, many drugs…

Expanding the Antibiotic Arsenal: A New Drug of Last Resort

Vancomycin-resistant Enterococcus. Photo Credit: Janice Haney Carr Content Providers: CDC. Prior to the discovery of antibiotics, bacterial infections were the leading cause of death worldwide. Now, treating infections is often a routine procedure –…

Microbial Physicians: Delivering drugs with bacteria

by Benika Pinch Fancy a pill packed with bacteria? Researchers are investigating using genetically modified bacteria, taken in pill form, to treat human disease. Informally, they are called “designer probiotics”. But, unlike probiotics (microorganisms…