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dna

Cellular Secrets: Getting a look at how cells repair DNA

Before cells divide, they have to unwind their chromosomes, copy of all of their DNA, and then wrap the DNA backup into chromosomes. When this process happens, cells often lose a little bit of DNA from the tips of their chromosomes. An enzyme, called…

You are unique - Does your gene editing treatment need to be too?

Many diseases are caused by genetic mutations. Small mutations can cause certain cancers, some cases of blindness, influence heart disease, and many other pathologies. A new and powerful technology called CRISPR-Cas9 aims to correct for these genetic…

All Wound Up: DNA sequencing reveals the 3D structure of our DNA

by Gemma Johnson figures by Olivia Foster You might remember being in a biology class where molecular biology is often represented by cartoons in bright colors on the pages of a textbook. What’s happening inside our cells, however, is much more…

Expanding the genetic alphabet

Since the beginning of time, the genetic alphabet in all living things has consisted of 4 letters. Now, scientists have discovered a way to expand the genetic code to store and use orders of magnitude more information than ever before. Deoxyribonucleic…

How stress can change your DNA

A first link between chronic stress, genetics, and mental illness has recently observed in mice. Researchers have discovered that the genes of mice exposed to chronic stress change over time. Modifications were most associated with genes related to a…

CRISPR 2.0: Genome engineering made easy as A-B-C

CRISPR 2.0 is causing quite the ruckus in the scientific community. Why? Imagine that you had written a note in permanent marker, but later decided you wanted to change a single word. Without the ability to erase, your options would be limited, and…

Catching Cancer: Blood Test for Early-Stage Diagnosis

What is the difference between a normal cell and a cancer cell? The answer lies in their DNA. Cancer results from the accumulation of genetic mutations, which trigger uncontrolled cell growth. Cancer’s mutated DNA can reveal its presence early on in…

Cancer Moonshot Musings II: Fusion oncoproteins in focus

by Steph Guerra figures by Shannon McArdel The Cancer Moonshot is an initiative that was launched by Joe Biden in 2016 with the goal of accelerating cancer research progress by bringing together world-class researchers and institutions in the battle…

Could Woolly Mammoths Walk Again?

The Church lab at Harvard University recently announced plans to create a hybrid mammoth and elephant. Using a technology called CRISPR, researchers in the Church lab have learned how to insert mammoth DNA into the cells of modern elephants.…