CRISPR

CRISPR is a highly effective immune system that defends bacteria from viruses. It was recently shown that some viruses have evolved counter-defenses that protect their DNA with a nucleus-like structure.

CRISPR genome editing has been used to study the biology of a number of species, but its use in reptiles has been difficult to achieve. Scientists have now figured this out, and albino lizards are the product! Read Ben Andreone's article to learn more!

Cancer immunotherapy exploits our immune system to kill cancerous cells. Recently, researchers have discovered a novel way to do this. They engineered cells that are programmed to die and injected them into tumor. They have successfully shown that the…

by Valentina Lagomarsino figures by Sean Wilson Nearly four months ago, Chinese researcher He Jiankui announced that he had edited the genes of twin babies with CRISPR. CRISPR, also known as CRISPR/Cas9, can be thought of as “genetic scissors” that can…

by Michael Vinyard figures by Nicholas Lue Most therapeutic drug candidates that are put through clinical trials fail. Given that most of these fail during early development, the cost of bringing a single drug to market is now over $2.5 billion. If we…

While you are likely familiar with the annoying experience of being a mosquito’s ‘meal of the day’, more is going on behind the scenes of that insect bite than meets the eye.  Mosquitoes, which are drawn to human scent and breath, require proteins from…

In December 2018, a Chinese researcher, He Jiankui, shocked the world when he revealed the birth of the world’s first genetically edited babies. While it is clear that Jiankui egregiously violated university regulations and ethical standards, his…

A Chinese researcher, He Jiankui, shocked the world two weeks ago when he revealed that the world’s first genetically edited babies had been born. Jiankui claimed to have edited embryos before implanting them into the mother as part of an otherwise…

In an exciting step forward, dogs with Duchenne muscular dystrophy (DMD) were treated with the CRISPR genome editor to restore production of the missing protein responsible for the disease. After more studies to prove it is safe and effective long-term,…

by Jessalyn Ubellacker figure by Jovana Andrejevic Between September 1999 and June 2000, the first human genome was sequenced. Since then, scientists have learned not only to read the human genome, but also to manipulate it, offering unprecedented…