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Antibiotic Resistance

Antibiotic Persistence and Resistance

by Molly Sargen Antibiotics are drugs that kill or inhibit the growth of microbes, including bacteria and fungi. These drugs work by blocking essential processes like protein production, DNA replication, and cell division. After Alexander Fleming’s…

How COVID-19 is Shaping Antibiotic Resistance

by Molly Sargenfigures by Molly Sargen, Buse Aktaş, and Aparna Nathan COVID-19 is unarguably devastating from any perspective. Even as we struggle to overcome the present challenges of the pandemic, COVID-19 is paving the way for other infectious…

Antibiotic uses multiple mechanisms to avoid resistance

Researchers developed a molecule that targets bacterial cells by two different mechanisms--attacking the cell membrane and disabling folate synthesis. This molecule seems to prevent bacteria from developing antibiotic-resistance.

Artificial Intelligence - our new MVP against infections?

In order to combat the growing problem of antibiotic resistance, a group of scientists from MIT are using artificial intelligence to discover new and effective antibiotics. They were able to predict a powerful new antibiotic compound that is effective…

Superbug Treatments Live in the Dirt

by Gregory Brunette figures by Daniel Utter Every year, new biology students dig for tiny, bacteria-infecting viruses called phages. Short for bacteriophages, these ubiquitous viruses thrive unseen in the world around us, replicating endlessly through…

The Quest for Better Bandages Turns to Nanofibers

Our skin is a protective barrier to bacterial infection, but damage to the skin allows bacteria to enter. Normally, our immune system kills the bacteria and allows wounds to heal. However, certain diseases can overload the immune system and lead to heavy…

Less of the Same: Rebooting the antibiotic pipeline

by Francesca Tomasi figures by Aparna Nathan Too Much of a Good Thing? Ninety years ago, Alexander Fleming happened upon the chemical compound penicillin and sparked a medical revolution. It was a serendipitous occasion – Fleming had been growing plates…

Bacteriophage: A solution to our antibiotics problem?

by Veerasak “Jeep” Srisuknimit figures by Jovana Andrejevic Our time with antibiotics is running out. In 2016, a woman in Nevada died from a bacterial infection caused by Klebsiella pneumoniae that was resistant to all available antibiotics. Bacteria…

Expanding the Antibiotic Arsenal: A New Drug of Last Resort

Vancomycin-resistant Enterococcus. Photo Credit: Janice Haney Carr Content Providers: CDC. Prior to the discovery of antibiotics, bacterial infections were the leading cause of death worldwide. Now, treating infections is often a routine procedure –…