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Alzheimer’s disease

New blood-based markers for dementia risk identified

New markers for dementia risk could pave the way for the development of blood-based methods for diagnosing and screening for dementia. This provides an opportunity to identify and diagnose at-risk populations earlier.

Are microglia the hero or the villain in Alzheimer’s disease?

by Gizem Terzioglufigures by MJ Park Alzheimer’s disease is a progressive neurodegenerative disorder that affects millions of people worldwide, and despite years of research efforts, there is still no cure. However, recent studies have highlighted the…

Microglia: The protectors of the brain

by Muhammet M. Ozturkfigures by Wei Wu For decades, scientists have been intrigued by how the brain controls the body. This curiosity led them to discover neurons, the brain’s messenger cells. Neurons, which receive, transmit, and process information,…

Slowing ALS with a Two-Drug Therapy

Results from a phase 2 clinical trial reveal that a new two-drug therapy for ALS can slow disease progression by six weeks over a six-month period. This therapy could possibly improve lifespan and quality of life, and may be effective in other…

A Radical New Mechanism for Cell Damage

Scientists have uncovered a new mechanism by which important components of cells can be damaged. Such a discovery could provide new insight into the biology of aging, cancer, and degeneration, as well as development of new drugs and strategies for food…

Learning to Remember: Memory-Trace Cells

Electrical recordings from human subjects have revealed the existence of memory-trace cells, which change their response depending on which previous experience is supposed to be recalled, providing a major insight into how the brain remembers specific…

Mathematical Modeling to Treat Degenerative Diseases

Drugs that inhibit formation of protein clumps may help treat degenerative diseases, but determining when to administer them is challenging. Using mathematical modelling, researchers have developed a strategy to design better treatment protocols based on…