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Archive: 2018

A major obstacle to CRISPR/Cas9 - preexisting immunity

The discovery of CRISPR/Cas9 is one of the biggest scientific breakthroughs in recent memory. This technology, first discovered in microbes, enables the cleaving of DNA in order to remove or replace existing genes. For a crash course into the history of…

Colonies 3

It may be hard to believe, but this sea of shiny, donut-shaped colonies are Pseudomonas aeruginosa colonies. These Pseudomonas colonies have a genetic mutation that causes many of the bacteria’s genes to be shut off. The donut-shape of these colonies may…

You are unique - Does your gene editing treatment need to be too?

Many diseases are caused by genetic mutations. Small mutations can cause certain cancers, some cases of blindness, influence heart disease, and many other pathologies. A new and powerful technology called CRISPR-Cas9 aims to correct for these genetic…

Colonies 1 and 2

No one likes to be in crowded spaces, so when colonies reach a critical cell density, cells within the colony begin to lyse, dramatically changing the architecture of the colony. The colony on the left is a wild-type colony, while the colony on the right…

Arctic Apples: A fresh new take on genetic engineering

by Allison Baker figures by Lillian Horin The Arctic apple is the juiciest newcomer to produce aisles. It has the special ability to resist browning after being cut (Figure 1), which protects its flavor and nutritional value. Browning also contributes to…

Ian Hill

My name is Ian Hill. I am from Winston-Salem, North Carolina, where I was born and raised.  My passion for biology began in the gardens of my family members. My grandmother was a passionate flower gardener, the head of a local garden club, and my dad…

Colonies on a Plate

A single bacterial cell is invisible to the naked eye. As that single cell grows and divides into new cells, however, it forms a visible pile of bacteria. In microbiology, we call this pile of bacteria a colony. A colony’s appearance can indicate a lot…